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Irritable Bowel Syndrome (IBS)

Original price was: ₹5,160.Current price is: ₹4,591.

The AutoimmunityCare IBS Bundle is a clinically formulated, gut-healing supplement protocol designed to target the root causes of Irritable Bowel Syndrome — not just symptoms. This bundle supports digestion, reduces bloating, calms inflammation, restores microbial balance, and strengthens the gut lining. It combines premium probiotics, digestive enzymes, gut-lining nutrients, and anti-inflammatory botanicals to help you regain digestive comfort and restore healthy bowel patterns.

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Understanding Irritable Bowel Syndrome: A Comprehensive Guide

Irritable Bowel Syndrome (IBS) is a common functional gastrointestinal disorder characterized by chronic abdominal pain, bloating, and altered bowel habits in the absence of identifiable structural or biochemical abnormalities (Latif et al., 2020; Mayer, 2008). It affects 10–20% of adults and adolescents worldwide, with women being disproportionately affected—14–24% in females and 5–19% in males (Coss-Adame & Rao, 2014; Longstreth et al., 2006; Al-Attar, 2020).

IBS is diagnosed using the ROME IV Criteria, which defines IBS as:

• Recurrent abdominal pain, at least 1 day per week for the last 3 months, associated with two or more of the following:
• Related to defecation
• Associated with change in stool frequency
• Associated with change in stool form (Ng et al., 2023)

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What we have in Irritable Bowel Syndrome (IBS)

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IBS is multifactorial, involving interactions between the gut, nervous system, immune system, and microbiome. Key contributors include: ● Abnormal gut motility: These patients may have increased or decreased movement of the gut that can lead to diarrhea and constipation. ● Visceral hypersensitivity - These patients may have increased sensitivity to pain in the internal organs. Therefore, even normal amounts of gas or stool can cause discomfort. ● Brain-gut dysfunction - The brain and gut communicate with each other through biochemical signalling and nerve pathways. Any disturbance of this can cause IBS symptoms. ● Gut dysbiosis - alteration in gut microbiota composition has been observed in IBS patients. ● Genetic factors - IBS patients are likely to have a family history, suggesting a genetic component (Holtmann et al., 2016). ● Psychological Factors - Anxiety, depression, and stress can trigger or worsen IBS symptoms (Ferreira et al., 2019; Mayer et al., 2023). ● Food sensitivities - Some patients are sensitive to certain food groups like gluten, FODMAPS (carbohydrates), dairy that can trigger IBS symptoms. ● Infections and inflammation - Prior infections and inflammation in the gut may contribute to the development of IBS (Shaikh et al., 2023).

IBS is classified into four types based on the stool consistency : ● IBS-C : Constipation predominant ● IBS-D : Diarrhoea predominant. ● IBS-M : Mixed bowel habits. ● IBS-U : Undefined; symptoms vary. Other clinical features of IBS include : ● Abdominal pain ● Abdominal discomfort ● Bloating ● Excessive gas ● Urgency before bowel movements ● Sensation of incomplete emptying of bowels ● Mucus in stools ● Nausea ● Fatigue ● Anxiety and mood disorders (Karantanos et al., 2010).

For diarrhoea predominant IBS, antidiarrheal medications like loperamide can be used. Laxatives and motility improving drugs are used in the constipation predominant subtype. Antispasmodic medications and low-dose antidepressants, can be used for pain management in these patients.

Functional Medicine Perspective on IBS IBS is not “only in the gut.” It is a systems condition, driven by gut-brain axis imbalance, microbiome disruption, food sensitivities, stress biology, and impaired digestion. Functional medicine focuses on identifying and correcting root causes such as: • Dysbiosis (bacterial imbalance) • SIBO (small intestinal bacterial overgrowth) • Gut permeability ("leaky gut") • Food intolerances • Chronic stress and HPA-axis dysfunction • Hypochlorhydria (low stomach acid) • Nutrient deficiencies (B12, iron, magnesium) Dietary Remedies: Foods to avoid: • In general, it is important to avoid sugars, gluten, dairy, refined carbohydrates, and processed foods. • High FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) foods like apple, mango, watermelon, garlic, onion, cauliflower, cabbage, mushroom, dairy products like milk, yogurt and ice cream, lentils, chickpeas, beans, wheat, barley, sweeteners etc. • Carbonated drinks, chewing gum, hard candies. Diet must be personalized, as triggers vary widely. • Low-FODMAP diet (one of the most researched interventions) • Reducing gluten, dairy, onions, garlic, legumes, cruciferous vegetables (as needed) • Avoiding alcohol, caffeine, artificial sweeteners • Increasing water intake • Adjusting fiber type (soluble often better tolerated than insoluble) Lifestyle Remedies: Regular physical exercise and stress reduction techniques like yoga and meditation can help alleviate overall IBS symptoms. It is important to make necessary diet changes which may be different for each individual. Avoid symptom triggering foods, such as high-FODMAP foods or gluten. Reduce intake of alcohol, caffeine, onion, garlic, legumes, cruciferous vegetables like broccoli and cabbage and dairy that may worsen symptoms. Increase water intake, and eat smaller, more frequent meals to improve digestion. Fiber intake can be tricky in IBS and often needs to be adjusted based on individual tolerance through trial and error.

IBS natural treatment supplements: 1. Probiotics Evidence supports specific strains like L. rhamnosus GG and S. boulardii for reducing symptoms and supporting microbial balance. 2. Peppermint Oil Clinically shown to reduce global IBS symptoms (Alammar et al., 2019). 3. L-Glutamine Supports gut barrier repair—useful for IBS-D and “leaky gut.” 4. Psyllium Husk A gentle soluble fiber helpful in IBS-C and IBS-M. 5. Polymethylsiloxane Polyhydrate Helps absorb gas and reduce bloating. 6. Vitamin D Low vitamin D is associated with higher IBS severity; supplementation may improve symptoms.

BS usually does not cause structural damage, but red flags should never be ignored: • Unintentional weight loss • Rectal bleeding • Persistent vomiting • Onset after age 50 • Family history of IBD, celiac disease, or colon cancer

Reference

Alammar, N., Wang, L., Saberi, B., Nanavati, J., Holtmann, G., Shinohara, R. T., & Mullin, G. E. (2019). The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. BMC Complementary and Alternative Medicine, 19(1). https://doi.org/10.1186/s12906-018-2409-0

Coss‐Adame, E., & Rao, S. S. C. (2014). Brain and Gut Interactions in Irritable Bowel Syndrome: New Paradigms and New Understandings [Review of Brain and Gut Interactions in Irritable Bowel Syndrome: New Paradigms and New Understandings]. Current Gastroenterology Reports, 16(4). Springer Science+Business Media. https://doi.org/10.1007/s11894-014-0379-z

Ferreira, A. I., Garrido, M., & Castro-Poças, F. (2019). Irritable Bowel Syndrome: News from an Old Disorder [Review of Irritable Bowel Syndrome: News from an Old Disorder]. GE Portuguese Journal of Gastroenterology, 27(4), 255. Karger Publishers. https://doi.org/10.1159/000503757

Holtmann, G., Ford, A. C., & Talley, N. J. (2016). Pathophysiology of irritable bowel syndrome. The Lancet. Gastroenterology & Hepatology, 1(2), 133. https://doi.org/10.1016/s2468-1253(16)30023-1

Karantanos, T., Markoutsaki, T., Gazouli, M., Anagnou, N. P., & Karamanolis, D. G. (2010). Current insights into the pathophysiology of Irritable Bowel Syndrome. Gut Pathogens, 2(1). https://doi.org/10.1186/1757-4749-2-3

Latif, A., Memon, F. A., & Asad, M. (2020). Irritable Bowel Syndrome in a Population of a Developing Country: Prevalence and Association. Cureus. https://doi.org/10.7759/cureus.8112

Longstreth, G. F., Thompson, W., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. E. (2006). Functional Bowel Disorders [Review of Functional Bowel Disorders]. Gastroenterology, 130(5), 1480. Elsevier BV. https://doi.org/10.1053/j.gastro.2005.11.061

Mayer, E. A. (2008). Irritable Bowel Syndrome [Review of Irritable Bowel Syndrome]. New England Journal of Medicine, 358(16), 1692. Massachusetts Medical Society. https://doi.org/10.1056/nejmcp0801447

Mayer, E. A., Ryu, H. J., & Bhatt, R. R. (2023). The neurobiology of irritable bowel syndrome [Review of The neurobiology of irritable bowel syndrome]. Molecular Psychiatry, 28(4), 1451. Springer Nature. https://doi.org/10.1038/s41380-023-01972-w

Ng, Q. X., Yau, C. E., Yaow, C. Y. L., Chong, R. I. H., Chong, N. Z.-Y., Teoh, S. E., Lim, Y. L., Soh, A. Y. S., Ng, W. K., & Thumboo, J. (2023). What Has Longitudinal ‘Omics’ Studies Taught Us about Irritable Bowel Syndrome? A Systematic Review [Review of What Has Longitudinal ‘Omics’ Studies Taught Us about Irritable Bowel Syndrome? A Systematic Review]. Metabolites, 13(4), 484. Multidisciplinary Digital Publishing Institute. https://doi.org/10.3390/metabo13040484

Shaikh, S. D., Sun, N., Canakis, A., Park, W. Y., & Weber, H. C. (2023). Irritable Bowel Syndrome and the Gut Microbiome: A Comprehensive Review [Review of Irritable Bowel Syndrome and the Gut Microbiome: A Comprehensive Review]. Journal of Clinical Medicine, 12(7), 2558. Multidisciplinary Digital Publishing Institute. https://doi.org/10.3390/jcm12072558

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